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Designing and computational analyzing of chimeric long-lasting GLP-1 receptor agonists for type 2 diabetes
Glucagon-like peptide-1 (GLP-1) is an intestinally derived incretin that plays a vital role in engineering the biological circuit involved in treating type 2 diabetes. Exceedingly short half-life (1–2 min) of GLP-1 limits its therapeutic applicability, and the implication of its new variants is unde...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584922/ https://www.ncbi.nlm.nih.gov/pubmed/37853095 http://dx.doi.org/10.1038/s41598-023-45185-1 |