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Integrated single-cell and bulk RNA sequencing analysis identified pyroptosis-related signature for diagnosis and prognosis in osteoarthritis

Osteoarthritis (OA), a degenerative disease of the joints, has one of the highest disability rates worldwide. This study investigates the role of pyroptosis-related genes in osteoarthritis and their expression in different chondrocyte subtypes at the individual cell level. Using OA-related datasets...

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Detalles Bibliográficos
Autores principales: Chen, Yanzhong, Zhang, Yaonan, Ge, Yongwei, Ren, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584952/
https://www.ncbi.nlm.nih.gov/pubmed/37853066
http://dx.doi.org/10.1038/s41598-023-44724-0