Quantitative analysis of prion disease using an AI-powered digital pathology framework

Prion disease is a fatal neurodegenerative disorder characterized by accumulation of an abnormal prion protein (PrPSc) in the central nervous system. To identify PrPSc aggregates for diagnostic purposes, pathologists use immunohistochemical staining of prion protein antibodies on tissue samples. Wit...

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Detalles Bibliográficos
Autores principales: Salvi, Massimo, Molinari, Filippo, Ciccarelli, Mario, Testi, Roberto, Taraglio, Stefano, Imperiale, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584956/
https://www.ncbi.nlm.nih.gov/pubmed/37853094
http://dx.doi.org/10.1038/s41598-023-44782-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584956/
https://www.ncbi.nlm.nih.gov/pubmed/37853094
http://dx.doi.org/10.1038/s41598-023-44782-4

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