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Quantitative analysis of prion disease using an AI-powered digital pathology framework
Prion disease is a fatal neurodegenerative disorder characterized by accumulation of an abnormal prion protein (PrPSc) in the central nervous system. To identify PrPSc aggregates for diagnostic purposes, pathologists use immunohistochemical staining of prion protein antibodies on tissue samples. Wit...
Autores principales: | Salvi, Massimo, Molinari, Filippo, Ciccarelli, Mario, Testi, Roberto, Taraglio, Stefano, Imperiale, Daniele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584956/ https://www.ncbi.nlm.nih.gov/pubmed/37853094 http://dx.doi.org/10.1038/s41598-023-44782-4 |
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