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GeneToCN: an alignment-free method for gene copy number estimation directly from next-generation sequencing reads
Genomes exhibit large regions with segmental copy number variation, many of which include entire genes and are multiallelic. We have developed a computational method GeneToCN that counts the frequencies of gene-specific k-mers in FASTQ files and uses this information to infer copy number of the gene...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584998/ https://www.ncbi.nlm.nih.gov/pubmed/37853040 http://dx.doi.org/10.1038/s41598-023-44636-z |