Intracellular Salmonella delivery of an exogenous immunization antigen refocuses CD8 T cells against cancer cells, eliminates pancreatic tumors and forms antitumor immunity

INTRODUCTION: Immunotherapies have shown great promise, but are not effective for all tumors types and are effective in less than 3% of patients with pancreatic ductal adenocarcinomas (PDAC). To make an immune treatment that is effective for more cancer patients and those with PDAC specifically, we...

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Detalles Bibliográficos
Autores principales: Raman, Vishnu, Howell, Lars M., Bloom, Shoshana M. K., Hall, Christopher L., Wetherby, Victoria E., Minter, Lisa M., Kulkarni, Ashish A., Forbes, Neil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585021/
https://www.ncbi.nlm.nih.gov/pubmed/37868996
http://dx.doi.org/10.3389/fimmu.2023.1228532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585021/
https://www.ncbi.nlm.nih.gov/pubmed/37868996
http://dx.doi.org/10.3389/fimmu.2023.1228532

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