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Transcriptional profiling of a fungal granuloma reveals a low metabolic activity of Paracoccidioides brasiliensis yeasts and an actively regulated host immune response

Granulomas are important immunological structures in the host defense against the fungus Paracoccidioides brasiliensis, the main etiologic agent of Paracoccidioidomycosis (PCM), a granulomatous systemic mycosis endemic in Latin America. We have performed transcriptional and proteomic studies of yeas...

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Detalles Bibliográficos
Autores principales: Borges, Bruno Montanari, Ramos, Rafael Berton Correia, Preite, Nycolas Willian, Kaminski, Valéria de Lima, Alves de Castro, Patrícia, Camacho, Maurício, Maximo, Marina Ferreira, Fill, Taicia Pacheco, Calich, Vera Lúcia Garcia, Traynor, Aimee M., Sarikaya-Bayram, Özlem, Doyle, Sean, Bayram, Özgür, de Campos, Claudia Barbosa Ladeira, Zelanis, André, Goldman, Gustavo H., Loures, Flávio Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585178/
https://www.ncbi.nlm.nih.gov/pubmed/37868350
http://dx.doi.org/10.3389/fcimb.2023.1268959