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Identification of small molecules that suppress cell invasion and metastasis promoted by WASF3 activation

The WASF3 gene promotes cancer cell invasion and metastasis, and genetic inactivation leads to suppression of metastasis. To identify small molecules that might interfere with WASF3 function, we performed an in silico docking study to the regulatory pocket of WASF3 using the National Cancer Institut...

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Detalles Bibliográficos
Autores principales: Silva, Jeane, Omar, Nivin, Sittaramane, Vinoth, Cowell, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585217/
https://www.ncbi.nlm.nih.gov/pubmed/37867831
http://dx.doi.org/10.1016/j.heliyon.2023.e20662