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Identification of small molecules that suppress cell invasion and metastasis promoted by WASF3 activation
The WASF3 gene promotes cancer cell invasion and metastasis, and genetic inactivation leads to suppression of metastasis. To identify small molecules that might interfere with WASF3 function, we performed an in silico docking study to the regulatory pocket of WASF3 using the National Cancer Institut...
Autores principales: | Silva, Jeane, Omar, Nivin, Sittaramane, Vinoth, Cowell, John K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585217/ https://www.ncbi.nlm.nih.gov/pubmed/37867831 http://dx.doi.org/10.1016/j.heliyon.2023.e20662 |
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