Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets

BACKGROUND: Malignant peripheral nerve sheath tumour (MPNST) is an aggressive orphan disease commonly affecting adolescents or young adults. Current knowledge of molecular tumour biology has been insufficient for development of rational treatment strategies. We aimed to discover molecular subtypes o...

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Detalles Bibliográficos
Autores principales: Høland, Maren, Berg, Kaja C.G., Eilertsen, Ina A., Bjerkehagen, Bodil, Kolberg, Matthias, Boye, Kjetil, Lingjærde, Ole Christian, Guren, Tormod K., Mandahl, Nils, van den Berg, Eva, Palmerini, Emanuela, Smeland, Sigbjørn, Picci, Piero, Mertens, Fredrik, Sveen, Anita, Lothe, Ragnhild A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585232/
https://www.ncbi.nlm.nih.gov/pubmed/37837931
http://dx.doi.org/10.1016/j.ebiom.2023.104829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585232/
https://www.ncbi.nlm.nih.gov/pubmed/37837931
http://dx.doi.org/10.1016/j.ebiom.2023.104829

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