Refined control of CRISPR-Cas9 gene editing in Clostridium sporogenes: the creation of recombinant strains for therapeutic applications

Despite considerable clinical success, the potential of cancer immunotherapy is restricted by a lack of tumour-targeting strategies. Treatment requires systemic delivery of cytokines or antibodies at high levels to achieve clinically effective doses at malignant sites. This is exacerbated by poor pe...

Descripción completa

Detalles Bibliográficos
Autores principales: Kubiak, Aleksandra M., Claessen, Luuk, Zhang, Yanchao, Khazaie, Khashayarsha, Bailey, Tom S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585264/
https://www.ncbi.nlm.nih.gov/pubmed/37869009
http://dx.doi.org/10.3389/fimmu.2023.1241632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585264/
https://www.ncbi.nlm.nih.gov/pubmed/37869009
http://dx.doi.org/10.3389/fimmu.2023.1241632

Ejemplares similares