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Refined control of CRISPR-Cas9 gene editing in Clostridium sporogenes: the creation of recombinant strains for therapeutic applications

Despite considerable clinical success, the potential of cancer immunotherapy is restricted by a lack of tumour-targeting strategies. Treatment requires systemic delivery of cytokines or antibodies at high levels to achieve clinically effective doses at malignant sites. This is exacerbated by poor pe...

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Detalles Bibliográficos
Autores principales:	Kubiak, Aleksandra M., Claessen, Luuk, Zhang, Yanchao, Khazaie, Khashayarsha, Bailey, Tom S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585264/ https://www.ncbi.nlm.nih.gov/pubmed/37869009 http://dx.doi.org/10.3389/fimmu.2023.1241632

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