Single cell RNA-sequencing analysis reveals that N-acetylcysteine partially reverses hepatic immune dysfunction in biliary atresia

BACKGROUND & AIMS: Our previous study indicated that CD177(+) neutrophil activation has a vital role in the pathogenesis of biliary atresia (BA), which is partially ameliorated by N-acetylcysteine (NAC) treatment. Here, we evaluated the clinical efficacy of NAC treatment and profiled liver-resid...

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Detalles Bibliográficos
Autores principales: Ye, Rongchen, Ma, Sige, Chen, Yan, Shan, Jiarou, Tan, Ledong, Su, Liang, Tong, Yanlu, Zhao, Ziyang, Chen, Hongjiao, Fu, Ming, Guo, Zhipeng, Zuo, Xiaoyu, Yu, Jiakang, Zhong, Wei, Zeng, Jixiao, Liu, Fei, Chai, Chenwei, Guan, Xisi, Wang, Zhe, Liu, Tao, Liang, Jiankun, Zhang, Yan, Shi, Hongguang, Wen, Zhe, Xia, Huimin, Zhang, Ruizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585304/
https://www.ncbi.nlm.nih.gov/pubmed/37869073
http://dx.doi.org/10.1016/j.jhepr.2023.100908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585304/
https://www.ncbi.nlm.nih.gov/pubmed/37869073
http://dx.doi.org/10.1016/j.jhepr.2023.100908

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