Enhanced molecular dynamic simulation studies unravel long-range effects caused by sequence variations and partner binding in RNA aptamers

Intrinsic flexibility and structural modularity are two common features of RNA molecules. Although functionally crucial, RNA plasticity often represents a major complication in high-resolution structural studies. To overcome this problem, RNAs may be rigidified through the complexation with high-aff...

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Detalles Bibliográficos
Autores principales: Autiero, Ida, Vitagliano, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585333/
https://www.ncbi.nlm.nih.gov/pubmed/37869259
http://dx.doi.org/10.1016/j.omtn.2023.102039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585333/
https://www.ncbi.nlm.nih.gov/pubmed/37869259
http://dx.doi.org/10.1016/j.omtn.2023.102039

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