Microsponge-derived mini tablets loaded with immunosuppressive agents: Pharmacokinetic investigation in human volunteers, cell viability and IVIVC correlation

Sirolimus, a potent immunosuppressant, has been demonstrated to have remarkable activity in inhibiting allograft rejection in transplantation. The objective of the study was to fabricate microsponge mini tablets with enhanced solubility and bioavailability. β-Cyclodextrin and NEOCEL C91 were selecte...

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Detalles Bibliográficos
Autores principales: Mehmood, Yasir, Shahid, Hira, Abbas, Muhammad, Farooq, Umar, Ali, Shaukat, Kazi, Mohsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585343/
https://www.ncbi.nlm.nih.gov/pubmed/37868642
http://dx.doi.org/10.1016/j.jsps.2023.101799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585343/
https://www.ncbi.nlm.nih.gov/pubmed/37868642
http://dx.doi.org/10.1016/j.jsps.2023.101799

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