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Hydrophobic moment drives penetration of bacterial membranes by transmembrane peptides

With antimicrobial resistance (AMR) remaining a persistent and growing threat to human health worldwide, membrane-active peptides are gaining traction as an alternative strategy to overcome the issue. Membrane-embedded multi-drug resistant (MDR) efflux pumps are a prime target for membrane-active pe...

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Detalles Bibliográficos
Autores principales: Johnson, Tyler S., Bourdine, Aleksandra A., Deber, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585379/
https://www.ncbi.nlm.nih.gov/pubmed/37734555
http://dx.doi.org/10.1016/j.jbc.2023.105266