Uncovering SOD3 and GPX4 as new targets of Benzo[α]pyrene-induced hepatotoxicity through Metabolomics and Chemical Proteomics

Benzo[α]pyrene (Bap) is recognized as a ubiquitous environmental pollutant among the polycyclic aromatic hydrocarbons (PAHs) class. Previous studies have shown that the hepatotoxicity of Bap is mainly caused by its metabolites, although it remains unclear whether Bap itself induces such damage. This...

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Detalles Bibliográficos
Autores principales: Wang, Yanwei, Zhao, Jiahui, Xu, Yipeng, Tao, Cimin, Tong, Jie, Luo, Yingjie, Chen, Yong, Liu, Xuesong, Xu, Tengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585396/
https://www.ncbi.nlm.nih.gov/pubmed/37847980
http://dx.doi.org/10.1016/j.redox.2023.102930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585396/
https://www.ncbi.nlm.nih.gov/pubmed/37847980
http://dx.doi.org/10.1016/j.redox.2023.102930

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