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Mapping the Direction of Nucleocytoplasmic Transport of Glucocorticoid Receptor (GR) in Live Cells Using Two-Foci Cross-Correlation in Massively Parallel Fluorescence Correlation Spectroscopy (mpFCS)

[Image: see text] Nucleocytoplasmic transport of transcription factors is vital for normal cellular function, and its breakdown is a major contributing factor in many diseases. The glucocorticoid receptor (GR) is an evolutionarily conserved, ligand-dependent transcription factor that regulates homeo...

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Detalles Bibliográficos
Autores principales: Nikolić, Stanko N., Oasa, Sho, Krmpot, Aleksandar J., Terenius, Lars, Belić, Milivoj R., Rigler, Rudolf, Vukojević, Vladana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585663/
https://www.ncbi.nlm.nih.gov/pubmed/37782779
http://dx.doi.org/10.1021/acs.analchem.3c01427