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Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy

New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis methods (microwave-assisted and grinding techniques). 4,6-Diamino-1,3-diphenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile (2) shows high anti-cancer activity against both Hep...

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Detalles Bibliográficos
Autores principales: Anwer, Kurls E., Sayed, Galal H., Essa, Basma M., Selim, Adli A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585773/
https://www.ncbi.nlm.nih.gov/pubmed/37853452
http://dx.doi.org/10.1186/s13065-023-01053-7