Cargando…

Green synthesis of highly functionalized heterocyclic bearing pyrazole moiety for cancer-targeted chemo/radioisotope therapy

New derivatives of heterocyclic bearing pyrazole moiety were synthesized (eight new compounds from 2 to 9) via green synthesis methods (microwave-assisted and grinding techniques). 4,6-Diamino-1,3-diphenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile (2) shows high anti-cancer activity against both Hep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anwer, Kurls E., Sayed, Galal H., Essa, Basma M., Selim, Adli A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585773/ https://www.ncbi.nlm.nih.gov/pubmed/37853452 http://dx.doi.org/10.1186/s13065-023-01053-7

Ejemplares similares

Synthesis and Cytotoxic Activity of Novel Tetrahydrocurcumin Derivatives Bearing Pyrazole Moiety
por: Mahal, Ahmed, et al.
Publicado: (2017)

Cytotoxic Effects of Newly Synthesized Heterocyclic Candidates Containing Nicotinonitrile and Pyrazole Moieties on Hepatocellular and Cervical Carcinomas
por: A. El-Sayed, Amira, et al.
Publicado: (2019)

Design, synthesis and evaluation of anticancer activity of novel 2-thioxoimidazolidin-4-one derivatives bearing pyrazole, triazole and benzoxazole moieties
por: Elhady, Heba A., et al.
Publicado: (2018)

Fused Triazinobenzimidazoles Bearing Heterocyclic Moiety: Synthesis, Structure Investigations, and In Silico and In Vitro Biological Activity
por: Anichina, Kameliya, et al.
Publicado: (2023)

Semisynthetic Derivatives of Pentacyclic Triterpenes Bearing Heterocyclic Moieties with Therapeutic Potential
por: Nistor, Gabriela, et al.
Publicado: (2022)

New metathesis catalyst bearing chromanyl moieties at the N-heterocyclic carbene ligand
por: Hryniewicka, Agnieszka, et al.
Publicado: (2015)

Uses of Cyanoacetylhydrazine in Heterocyclic Synthesis: Novel Synthesis of Pyrazole Derivatives with Anti-tumor Activities
por: Mohareb, Rafat M., et al.
Publicado: (2012)

Synthesis and antimicrobial activity of new series of thiazoles, pyridines and pyrazoles based on coumarin moiety
por: Sayed, Mariam T., et al.
Publicado: (2023)

Synthesis and Analgesic Activity of Some New Pyrazoles and Triazoles Bearing a 6,8-Dibromo-2-methylquinazoline Moiety
por: Saad, Hosam A., et al.
Publicado: (2011)

Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety
por: Castaño, Lina Fernanda, et al.
Publicado: (2022)

Synthesis of Novel Pyrazole Derivatives Containing Phenylpyridine Moieties with Herbicidal Activity
por: Cai, Zengfei, et al.
Publicado: (2022)

Synthesis and antioxidant, antimicrobial, and antiviral activity of some pyrazole-based heterocycles using a 2(3H)-furanone derivative
por: Youssef, Youssef M., et al.
Publicado: (2023)

Synthesis and Antimicrobial Evaluation of Some Novel Thiazole, Pyridone, Pyrazole, Chromene, Hydrazone Derivatives Bearing a Biologically Active Sulfonamide Moiety
por: Darwish, Elham S., et al.
Publicado: (2014)

Synthesis and Antibacterial Activity of Novel Curcumin Derivatives Containing Heterocyclic Moiety
por: A. Hamed, Othman, et al.
Publicado: (2013)

Editorial: Green Synthesis of Heterocycles
por: Aricò, Fabio
Publicado: (2020)

Direct N-heterocyclization of hydrazines to access styrylated pyrazoles: synthesis of 1,3,5-trisubstituted pyrazoles and dihydropyrazoles
por: Venkateswarlu, Vunnam, et al.
Publicado: (2018)

Synthesis and Antibacterial Evaluation of Novel Heterocyclic Compounds Containing a Sulfonamido Moiety
por: Azab, Mohammad Emad, et al.
Publicado: (2013)

New Betulin Derivatives with Nitrogen Heterocyclic Moiety—Synthesis and Anticancer Activity In Vitro
por: Bębenek, Ewa, et al.
Publicado: (2022)

Novel Pyrazole-Hydrazone Derivatives Containing an Isoxazole Moiety: Design, Synthesis, and Antiviral Activity
por: Yang, Zaibo, et al.
Publicado: (2018)

Synthesis and Bioactivities of Novel Pyrazole Oxime Derivatives Containing a 5-Trifluoromethylpyridyl Moiety
por: Dai, Hong, et al.
Publicado: (2016)

Dialkyl Carbonates in the Green Synthesis of Heterocycles
por: Tundo, Pietro, et al.
Publicado: (2019)

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (M(pro))
por: Abu-Melha, Sraa, et al.
Publicado: (2020)

Synthesis, and docking studies of novel heterocycles incorporating the indazolylthiazole moiety as antimicrobial and anticancer agents
por: Dawoud, Nadia T. A., et al.
Publicado: (2022)

Synthesis, spectroscopic, DFT calculations, biological activity, SAR, and molecular docking studies of novel bioactive pyridine derivatives
por: Anwer, Kurls E., et al.
Publicado: (2023)

Synthesis of Novel 3H-Quinazolin-4-ones Containing Pyrazolinone, Pyrazole and Pyrimidinone Moieties
por: Saleh, Mohamed A., et al.
Publicado: (2003)

Selective Synthesis of Bis-Heterocycles via Mono- and Di-Selenylation of Pyrazoles and Other Heteroarenes
por: Kour, Jaspreet, et al.
Publicado: (2022)

Design, Green Synthesis and Tailoring of Vitamin E TPGS Augmented Niosomal Nano-Carrier of Pyrazolopyrimidines as Potential Anti-Liver and Breast Cancer Agents with Accentuated Oral Bioavailability
por: Anwer, Kurls E., et al.
Publicado: (2022)

Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review
por: Siddiqui, Nadeem, et al.
Publicado: (2011)

Synthesis of Tricyclic Condensed Rings Incorporating the Pyrazole or Isoxazole Moieties Bonded to a 4-Piperidinyl Substituent
por: Pinna, Giansalvo, et al.
Publicado: (2013)

Design, Synthesis, and Biological Activities of Novel Pyrazole Oxime Compounds Containing a Substituted Pyridyl Moiety
por: Chen, Cuili, et al.
Publicado: (2017)

Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer
por: Tian, Longlong, et al.
Publicado: (2017)

Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety
por: Ugwu, David Izuchukwu, et al.
Publicado: (2018)

Synthesis and characterization of some novel diaryl urea derivatives bearing quinoxalindione moiety
por: Sadeghian-Rizi, Sedighe, et al.
Publicado: (2018)

Design, Synthesis, and Bioactivities of Novel Trifluoromethyl Pyrimidine Derivatives Bearing an Amide Moiety
por: Lan, Wenjun, et al.
Publicado: (2022)

Synthesis and Anticancer Evaluation of New Thiazole and Thiadiazole Derivatives Bearing Acetanilide Moiety
por: El-Rayyes, Ali, et al.
Publicado: (2022)

Synthesis and Evaluation of the Anti-Microbial Activity of New Heterocycles Containing the 1,3,4-Thiadiazole Moiety
por: Farghaly, Thoraya A., et al.
Publicado: (2011)

Synthesis of Novel 1-Oxo-2,3,4-trisubstituted Tetrahydroisoquinoline Derivatives, Bearing Other Heterocyclic Moieties and Comparative Preliminary Study of Anti-Coronavirus Activity of Selected Compounds
por: Kandinska, Meglena I., et al.
Publicado: (2023)

Radioisotope instruments
por: Cameron, J F, et al.
Publicado: (1971)

RADIOISOTOPE RENOGRAPHY
Publicado: (1963)

Radioisotope data
por: Allen, R A, et al.
Publicado: (1961)

Cannot write session to /tmp/vufind_sessions/sess_cb2tamm7bt45naqa2n045kf2hn