CircPTPN22 modulates T-cell activation by sponging miR-4689 to regulate S1PR1 expression in patients with systemic lupus erythematosus

BACKGROUND: Circular RNAs are involved in autoimmune disease pathogenesis. Our previous study indicated that circPTPN22 is involved in autoimmune diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis, but the underlying mechanisms remain unclear. METHODS: First, the expressio...

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Detalles Bibliográficos
Autores principales: Jiang, Zhuyan, Li, Shifei, Jia, Yuying, Wu, Qijun, Chen, Xuemeng, Zhang, Mengjie, Miao, Qingqing, Zhong, Zhiting, Zhai, Zhifang, Ni, Bing, Xiao, Jun, Tang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585821/
https://www.ncbi.nlm.nih.gov/pubmed/37858140
http://dx.doi.org/10.1186/s13075-023-03150-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585821/
https://www.ncbi.nlm.nih.gov/pubmed/37858140
http://dx.doi.org/10.1186/s13075-023-03150-3

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