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CircPTPN22 modulates T-cell activation by sponging miR-4689 to regulate S1PR1 expression in patients with systemic lupus erythematosus
BACKGROUND: Circular RNAs are involved in autoimmune disease pathogenesis. Our previous study indicated that circPTPN22 is involved in autoimmune diseases, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis, but the underlying mechanisms remain unclear. METHODS: First, the expressio...
Autores principales: | Jiang, Zhuyan, Li, Shifei, Jia, Yuying, Wu, Qijun, Chen, Xuemeng, Zhang, Mengjie, Miao, Qingqing, Zhong, Zhiting, Zhai, Zhifang, Ni, Bing, Xiao, Jun, Tang, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585821/ https://www.ncbi.nlm.nih.gov/pubmed/37858140 http://dx.doi.org/10.1186/s13075-023-03150-3 |
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