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Single-cell RNA sequencing reveals pro-invasive cancer-associated fibroblasts in hypopharyngeal squamous cell carcinoma

BACKGROUND: Hypopharyngeal squamous cell carcinoma (HPSCC) has the worst prognosis among all head-and-neck cancers, and treatment options are limited. Tumor microenvironment (TME) analysis can help identify new therapeutic targets and combined treatment strategies. METHODS: Six primary HPSCC tissues...

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Detalles Bibliográficos
Autores principales: Cai, Zhimou, Chen, Lin, Chen, Siyu, Fang, Ruihua, Chen, Xiaolin, Lei, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585865/
https://www.ncbi.nlm.nih.gov/pubmed/37853464
http://dx.doi.org/10.1186/s12964-023-01312-z