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Tumor microenvironment-responsive DNA-based nanomedicine triggers innate sensing for enhanced immunotherapy

Lack of proper innate sensing inside the tumor microenvironment could reduce both innate and adaptive immunity, which remains a critical cause of immunotherapy failure in various tumor treatments. Double-stranded DNA (dsDNA) has been evidenced to be a promising immunostimulatory agent to induce type...

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Detalles Bibliográficos
Autores principales: Li, Jinyang, Han, Xiaoyu, Gao, Shanshan, Yan, Yumeng, Li, Xiaoguang, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585899/
https://www.ncbi.nlm.nih.gov/pubmed/37858171
http://dx.doi.org/10.1186/s12951-023-02132-6