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The potent analgesia of intrathecal 2R, 6R-HNK via TRPA1 inhibition in LF-PENS-induced chronic primary pain model

BACKGROUND: Chronic primary pain (CPP) is an intractable pain of unknown cause with significant emotional distress and/or dysfunction that is a leading factor of disability globally. The lack of a suitable animal model that mimic CPP in humans has frustrated efforts to curb disease progression. 2R,...

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Detalles Bibliográficos
Autores principales: Liu, An-Ran, Lin, Zhen-Jia, Wei, Ming, Tang, Yuan, Zhang, Hui, Peng, Xiang-Ge, Li, Ying, Zheng, Yu-Fan, Tan, Zhi, Zhou, Li-Jun, Feng, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585932/
https://www.ncbi.nlm.nih.gov/pubmed/37858040
http://dx.doi.org/10.1186/s10194-023-01667-1