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Imaging Protein Aggregates in Parkinson’s Disease Serum Using Aptamer-Assisted Single-Molecule Pull-Down

[Image: see text] The formation of soluble α-synuclein (α-syn) and amyloid-β (Aβ) aggregates is associated with the development of Parkinson’s disease (PD). Current methods mainly focus on the measurement of the aggregate concentration and are unable to determine their heterogeneous size and shape,...

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Detalles Bibliográficos
Autores principales: Zhang, Yu P., Lobanova, Evgeniia, Emin, Derya, Lobanov, Sergey V., Kouli, Antonina, Williams-Gray, Caroline H., Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585954/
https://www.ncbi.nlm.nih.gov/pubmed/37782556
http://dx.doi.org/10.1021/acs.analchem.3c02515