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Imaging Protein Aggregates in Parkinson’s Disease Serum Using Aptamer-Assisted Single-Molecule Pull-Down
[Image: see text] The formation of soluble α-synuclein (α-syn) and amyloid-β (Aβ) aggregates is associated with the development of Parkinson’s disease (PD). Current methods mainly focus on the measurement of the aggregate concentration and are unable to determine their heterogeneous size and shape,...
Autores principales: | Zhang, Yu P., Lobanova, Evgeniia, Emin, Derya, Lobanov, Sergey V., Kouli, Antonina, Williams-Gray, Caroline H., Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585954/ https://www.ncbi.nlm.nih.gov/pubmed/37782556 http://dx.doi.org/10.1021/acs.analchem.3c02515 |
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