Newly Synthesized Anticancer Purine Derivatives Inhibiting p-EIF4E Using Surface-Modified Lipid Nanovesicles

[Image: see text] Translation of mRNA is one of the processes adopted by cancer cells to maintain survival via phosphorylated (p)-eIF4E overexpression. Once p-eIF4E binds to the cap structure of mRNA, it advocates a nonstop translation process. In this regard, 15 new-based GMP analogs were synthesiz...

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Detalles Bibliográficos
Autores principales: Attia, Reem T., Ewida, Menna A., Khaled, Eman, Fahmy, Sherif Ashraf, Fawzy, Iten M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586017/
https://www.ncbi.nlm.nih.gov/pubmed/37867723
http://dx.doi.org/10.1021/acsomega.3c02991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586017/
https://www.ncbi.nlm.nih.gov/pubmed/37867723
http://dx.doi.org/10.1021/acsomega.3c02991

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