Activation of mTORC1 Signaling Cascade in Hippocampus and Medial Prefrontal Cortex Is Required for Antidepressant Actions of Vortioxetine in Mice

BACKGROUND: Although thought of as a multimodal-acting antidepressant targeting the serotonin system, more molecules are being shown to participate in the antidepressant mechanism of vortioxetine. A previous report has shown that vortioxetine administration enhanced the expression of rapamycin compl...

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Detalles Bibliográficos
Autores principales: Li, Wei-Yu, Shi, Tian-Shun, Huang, Jie, Chen, Yan-Mei, Guan, Wei, Jiang, Bo, Wang, Cheng-Niu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586031/
https://www.ncbi.nlm.nih.gov/pubmed/37025079
http://dx.doi.org/10.1093/ijnp/pyad017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586031/
https://www.ncbi.nlm.nih.gov/pubmed/37025079
http://dx.doi.org/10.1093/ijnp/pyad017

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