Type 2 cytokines sensitize human sensory neurons to itch-associated stimuli

INTRODUCTION: Chronic itch is a central symptom of atopic dermatitis. Cutaneous afferent neurons express receptors interleukins (IL)-4, IL-13, and IL-33, which are type 2 cytokines that are elevated in atopic dermatitis. These neuronal cytokine receptors were found to be required in several murine m...

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Detalles Bibliográficos
Autores principales: Mack, Madison R., Miron, Yannick, Chen, Fanny, Miller, Paul E., Zhang, Annie, Korotzer, Andrew, Richman, Daniel, Bryce, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586051/
https://www.ncbi.nlm.nih.gov/pubmed/37868811
http://dx.doi.org/10.3389/fnmol.2023.1258823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586051/
https://www.ncbi.nlm.nih.gov/pubmed/37868811
http://dx.doi.org/10.3389/fnmol.2023.1258823

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