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Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells

Pseudoexfoliation glaucoma (PEXG) is characterized by dysregulated extracellular matrix (ECM) homeostasis that disrupts conventional outflow function and increases intraocular pressure (IOP). Prolonged IOP elevation results in optic nerve head damage and vision loss. Uniquely, PEXG is a form of open...

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Detalles Bibliográficos
Autores principales: Schmitt, Heather M, Hake, Kristyn M, Perkumas, Kristin M, Lê, Brandon M, Suarez, Maria F, De Ieso, Michael L, Rahman, Rashad S, Johnson, William M, Gomez-Caraballo, María, Ashley-Koch, Allison E, Hauser, Michael A, Stamer, W Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586201/
https://www.ncbi.nlm.nih.gov/pubmed/37540217
http://dx.doi.org/10.1093/hmg/ddad128