Cargando…

Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells

Pseudoexfoliation glaucoma (PEXG) is characterized by dysregulated extracellular matrix (ECM) homeostasis that disrupts conventional outflow function and increases intraocular pressure (IOP). Prolonged IOP elevation results in optic nerve head damage and vision loss. Uniquely, PEXG is a form of open...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmitt, Heather M, Hake, Kristyn M, Perkumas, Kristin M, Lê, Brandon M, Suarez, Maria F, De Ieso, Michael L, Rahman, Rashad S, Johnson, William M, Gomez-Caraballo, María, Ashley-Koch, Allison E, Hauser, Michael A, Stamer, W Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586201/ https://www.ncbi.nlm.nih.gov/pubmed/37540217 http://dx.doi.org/10.1093/hmg/ddad128

Ejemplares similares

Genetic background determines severity of Loxl1-mediated systemic and ocular elastosis in mice
por: Suarez, Maria F., et al.
Publicado: (2023)

Lysyl oxidase–like 2 (LOXL2)–mediated cross-linking of tropoelastin
por: Schmelzer, Christian E. H., et al.
Publicado: (2019)

Lysyl oxidase-like protein 1 (LOXL1) gene polymorphisms and exfoliation glaucoma in a Central European population
por: Mossböck, Georg, et al.
Publicado: (2008)

Specific protein 1(SP1) regulates the epithelial-mesenchymal transition via lysyl oxidase-like 2(LOXL2) in pancreatic ductal adenocarcinoma
por: Kim, Im-kyung, et al.
Publicado: (2019)

The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma
por: Liu, Yutao, et al.
Publicado: (2012)

Crystal structure of human lysyl oxidase-like 2 (hLOXL2) in a precursor state
por: Zhang, Xi, et al.
Publicado: (2018)

2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth
por: Smithen, Deborah A., et al.
Publicado: (2019)

Lysyl Oxidase Like-4 (LOXL4) as a tumor marker and prognosticator in advanced stage laryngeal cancer()
por: Altuntaş, Ozan Muzaffer, et al.
Publicado: (2021)

Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal
por: Ikenaga, Naoki, et al.
Publicado: (2017)

The Interactome of Cancer-Related Lysyl Oxidase and Lysyl Oxidase-Like Proteins
por: Vallet, Sylvain D., et al.
Publicado: (2020)

Changes in Circulating Lysyl Oxidase-Like-2 (LOXL2) Levels, HOMA, and Fibrosis after Sustained Virological Response by Direct Antiviral Therapy
por: Puente, Angela, et al.
Publicado: (2019)

LncRNA LOXL1-AS1 expression in cancer prognosis: A meta-analysis
por: Wang, Xuhua, et al.
Publicado: (2022)

Multifunctional Lysyl Oxidases
por: Trackman, Philip C.
Publicado: (2023)

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas
por: Moreno-Bueno, Gema, et al.
Publicado: (2011)

Variations in LOXL1 associated with exfoliation glaucoma do not affect amine oxidase activity
por: Kim, Seonkwan, et al.
Publicado: (2012)

LncRNA LOXL1-AS1 promotes esophageal squamous cell carcinoma progression by targeting DESC1
por: Li, Hongle, et al.
Publicado: (2021)

Origin and evolution of lysyl oxidases
por: Grau-Bové, Xavier, et al.
Publicado: (2015)

Lysyl Oxidase and the Tumor Microenvironment
por: Wang, Tong-Hong, et al.
Publicado: (2016)

Association of lysyl oxidase-like 1 gene polymorphisms with exfoliation syndrome in Koreans
por: Sagong, Min, et al.
Publicado: (2011)

Lysyl oxidase and hypoxia-inducible factor 1α: biomarkers of gastric cancer
por: Han, Ya-Lin, et al.
Publicado: (2019)

Serum lncRNA LOXL1‐AS1 is a diagnostic and prognostic marker for epithelial ovarian cancer
por: Liu, Chun‐Na, et al.
Publicado: (2020)

Development of novel LOXL1 genotyping method and evaluation of LOXL1, APOE and MTHFR polymorphisms in exfoliation syndrome/glaucoma in a Greek population
por: Chiras, Dimitrios, et al.
Publicado: (2013)

Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer
por: Nilsson, Maria, et al.
Publicado: (2016)

Physiologic Consequences of Caveolin-1 Ablation in Conventional Outflow Endothelia
por: De Ieso, Michael L., et al.
Publicado: (2020)

Role of Lysyl oxidase-like 1 gene polymorphisms in Pakistani patients with pseudoexfoliative glaucoma
por: Micheal, Shazia, et al.
Publicado: (2012)

Effects of parathyroid hormone (1-34) on the regulation of the lysyl oxidase family in ovariectomized mice
por: Cai, Linyi, et al.
Publicado: (2018)

Lysyl Oxidase Polymorphisms and Susceptibility to Osteosarcoma
por: Liu, Yang, et al.
Publicado: (2012)

An in situ activity assay for lysyl oxidases
por: Wang, Huilei, et al.
Publicado: (2021)

Serum Lysyl Oxidase Levels and Lysyl Oxidase Gene Polymorphism in Ovarian Cancer Patients of Eastern Indian Population
por: Kumari, Suchitra, et al.
Publicado: (2021)

LncRNA LOXL1-AS1 Promotes the Proliferation and Metastasis of Medulloblastoma by Activating the PI3K/AKT Pathway
por: Gao, Ran, et al.
Publicado: (2018)

Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function
por: Rosell-García, Tamara, et al.
Publicado: (2022)

Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma
por: Challa, Pratap, et al.
Publicado: (2008)

Serum lysyl oxidase concentration increases in long-standing systemic sclerosis: Can lysyl oxidase change over time?
por: Jokar, Mohammad Hassan, et al.
Publicado: (2021)

Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes
por: Liburkin-Dan, Tatyana, et al.
Publicado: (2022)

Evaluation of lysyl oxidase-like 1 gene polymorphisms in pseudoexfoliation syndrome in a Korean population
por: Park, Do Young, et al.
Publicado: (2013)

Association between Polymorphisms in Lysyl Oxidase-Like 1 and Susceptibility to Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma
por: Tang, Jun-Zhou, et al.
Publicado: (2014)

The role of lysyl oxidase-like 1 and fibulin-5 in the development of atherosclerosis and pelvic organ prolapse
por: Dal Moro, Fabrizio
Publicado: (2013)

Lysyl oxidase-like 1 polymorphisms in a southwestern Greek cataract population with pseudoexfoliation syndrome
por: Panoutsopoulos, Alexios A, et al.
Publicado: (2016)

Lysyl oxidase-like 1 deficiency alters ultrastructural and biomechanical properties of the peripapillary sclera in mice
por: Wareham, Lauren K., et al.
Publicado: (2022)

Prevalence of risk alleles in the lysyl oxidase-like 1 gene in pseudoexfoliation glaucoma patients in India
por: Vallabh, Neeru A, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_tfaj2b2ece1vi0in4ndpjb901m