Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting Plasmodium falciparum Hsp90

[Image: see text] Plasmodium falciparum causes the most lethal and widespread form of malaria. Eradication of malaria remains a priority due to the increasing number of cases of drug resistance. The heat shock protein 90 of P. falciparum (PfHsp90) is a validated drug target essential for parasite su...

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Detalles Bibliográficos
Autores principales: Mafethe, Ofentse, Ntseane, Tlhalefo, Dongola, Tendamudzimu Harmfree, Shonhai, Addmore, Gumede, Njabulo Joyfull, Mokoena, Fortunate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586269/
https://www.ncbi.nlm.nih.gov/pubmed/37867657
http://dx.doi.org/10.1021/acsomega.3c04494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586269/
https://www.ncbi.nlm.nih.gov/pubmed/37867657
http://dx.doi.org/10.1021/acsomega.3c04494

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