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Long non‑coding RNA L13Rik promotes high glucose-induced mesangial cell hypertrophy and matrix protein expression by regulating miR-2861/CDKN1B axis

BACKGROUND: Diabetic nephropathy (DN) is a frequent microvascular complication of diabetes. Glomerular mesangial cell (MC) hypertrophy occurs at the initial phase of DN and plays a critical role in the pathogenesis of DN. Given the role of long non coding RNA (lncRNA) in regulating MC hypertrophy an...

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Detalles Bibliográficos
Autores principales: Sun, Linlin, Ding, Miao, Chen, Fuhua, Zhu, Dingyu, Xie, Xinmiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586299/
https://www.ncbi.nlm.nih.gov/pubmed/37868060
http://dx.doi.org/10.7717/peerj.16170