Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds

[Image: see text] Dirhodium(II,II) paddlewheel catalysts were evaluated in silyl-hydrogen insertion reactions of aryl diazo compounds generated from o-nosyl hydrazones. The high reactivity of aryl diazo compounds necessitates their in situ generation from sulfonyl-protected hydrazones. Herein, we de...

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Autores principales: Abshire, Anthony, Ogunyemi, Bukola, Darko, Ampofo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586302/
https://www.ncbi.nlm.nih.gov/pubmed/37867650
http://dx.doi.org/10.1021/acsomega.3c03519
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author Abshire, Anthony
Ogunyemi, Bukola
Darko, Ampofo
author_facet Abshire, Anthony
Ogunyemi, Bukola
Darko, Ampofo
author_sort Abshire, Anthony
collection PubMed
description [Image: see text] Dirhodium(II,II) paddlewheel catalysts were evaluated in silyl-hydrogen insertion reactions of aryl diazo compounds generated from o-nosyl hydrazones. The high reactivity of aryl diazo compounds necessitates their in situ generation from sulfonyl-protected hydrazones. Herein, we describe our efforts to evaluate this transformation utilizing Rh(II) catalysts, including those with tethered, axially coordinating ligands. The heteroleptic catalyst, Rh(2)(OAc)(3)(2-OX), provided the highest yield of silanes when dioxane was the solvent.
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spelling pubmed-105863022023-10-20 Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds Abshire, Anthony Ogunyemi, Bukola Darko, Ampofo ACS Omega [Image: see text] Dirhodium(II,II) paddlewheel catalysts were evaluated in silyl-hydrogen insertion reactions of aryl diazo compounds generated from o-nosyl hydrazones. The high reactivity of aryl diazo compounds necessitates their in situ generation from sulfonyl-protected hydrazones. Herein, we describe our efforts to evaluate this transformation utilizing Rh(II) catalysts, including those with tethered, axially coordinating ligands. The heteroleptic catalyst, Rh(2)(OAc)(3)(2-OX), provided the highest yield of silanes when dioxane was the solvent. American Chemical Society 2023-10-06 /pmc/articles/PMC10586302/ /pubmed/37867650 http://dx.doi.org/10.1021/acsomega.3c03519 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Abshire, Anthony
Ogunyemi, Bukola
Darko, Ampofo
Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds
title Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds
title_full Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds
title_fullStr Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds
title_full_unstemmed Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds
title_short Rh(II)-Catalyzed Si–H Insertion with Nosyl-hydrazone-Protected Aryl Donor Diazo Compounds
title_sort rh(ii)-catalyzed si–h insertion with nosyl-hydrazone-protected aryl donor diazo compounds
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586302/
https://www.ncbi.nlm.nih.gov/pubmed/37867650
http://dx.doi.org/10.1021/acsomega.3c03519
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