Novel Acrylate-Based Derivatives: Design, Synthesis, Antiproliferative Screening, and Docking Study as Potential Combretastatin Analogues

[Image: see text] A variety of 3-(4-chlorophenyl) acrylic acids 4a,b and 3-(4-chlorophenyl)acrylate esters 5a–i were synthesized and structurally proven by spectroscopic studies such as IR, (1)H NMR, and (13)C NMR as well as mass spectrometry. All substances were investigated for their antiprolifera...

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Detalles Bibliográficos
Autores principales: Fayad, Eman, Altalhi, Sarah Awwadh, Abualnaja, Matokah M., Alrohaimi, Abdulmohsen H., Elsaid, Fahmy G., Abu Almaaty, Ali H., Saleem, Rasha Mohammed, Bazuhair, Mohammed A., Ahmed Maghrabi, Ali Hassan, Beshay, Botros Y., Zaki, Islam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586439/
https://www.ncbi.nlm.nih.gov/pubmed/37867686
http://dx.doi.org/10.1021/acsomega.3c05051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586439/
https://www.ncbi.nlm.nih.gov/pubmed/37867686
http://dx.doi.org/10.1021/acsomega.3c05051

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