Screening of Multitarget-Directed Natural Compounds as Drug Candidates for Alzheimer’s Disease Using In Silico Techniques: Their Extraction and In Vitro Validation

[Image: see text] Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs neurocognitive function. Acetylcholinesterase (AChE) and β-site APP cleaving enzyme 1 (BACE1) are the two main proteins implicated in AD. Indeed, the major available commercial drugs (donepezil, rivastigmine, and...

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Detalles Bibliográficos
Autores principales: Srivastava, Sukriti, Sharma, Shilpa, Deep, Shashank, Khare, Sunil Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586450/
https://www.ncbi.nlm.nih.gov/pubmed/37867692
http://dx.doi.org/10.1021/acsomega.3c04261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586450/
https://www.ncbi.nlm.nih.gov/pubmed/37867692
http://dx.doi.org/10.1021/acsomega.3c04261

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