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Screening of Multitarget-Directed Natural Compounds as Drug Candidates for Alzheimer’s Disease Using In Silico Techniques: Their Extraction and In Vitro Validation
[Image: see text] Alzheimer’s disease (AD) is a neurodegenerative disorder that impairs neurocognitive function. Acetylcholinesterase (AChE) and β-site APP cleaving enzyme 1 (BACE1) are the two main proteins implicated in AD. Indeed, the major available commercial drugs (donepezil, rivastigmine, and...
Autores principales: | Srivastava, Sukriti, Sharma, Shilpa, Deep, Shashank, Khare, Sunil Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586450/ https://www.ncbi.nlm.nih.gov/pubmed/37867692 http://dx.doi.org/10.1021/acsomega.3c04261 |
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