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Cortical spheroid on perfusable microvascular network in a microfluidic device

Human induced pluripotent stem cell (hiPSC)-derived brain spheroids can recapitulate the complex cytoarchitecture of the brain, as well as the genetic/epigenetic footprint of human brain development. However, hiPSC-derived 3D models such as spheroid and organoids does not have a perfusable microvasc...

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Detalles Bibliográficos
Autores principales: Russell, Teal, Dirar, Qassim, Li, Yan, Chiang, Chiwan, Laskowitz, Daniel T., Yun, Yeoheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586606/
https://www.ncbi.nlm.nih.gov/pubmed/37856438
http://dx.doi.org/10.1371/journal.pone.0288025