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Identification of preclinical dementia according to ATN classification for stratified trial recruitment: A machine learning approach

INTRODUCTION: The Amyloid/Tau/Neurodegeneration (ATN) framework was proposed to identify the preclinical biological state of Alzheimer’s disease (AD). We investigated whether ATN phenotype can be predicted using routinely collected research cohort data. METHODS: 927 EPAD LCS cohort participants free...

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Detalles Bibliográficos
Autores principales: Koychev, Ivan, Marinov, Evgeniy, Young, Simon, Lazarova, Sophia, Grigorova, Denitsa, Palejev, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586674/
https://www.ncbi.nlm.nih.gov/pubmed/37856502
http://dx.doi.org/10.1371/journal.pone.0288039