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Wnt10b protects cardiomyocytes against doxorubicin-induced cell death via MAPK modulation
BACKGROUND: Doxorubicin, an anthracycline chemotherapeutic known to incur heart damage, decreases heart function in up to 11% of patients. Recent investigations have implicated the Wnt signaling cascade as a key modulator of cardiac tissue repair after myocardial infarction. Wnt upregulation in muri...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586692/ https://www.ncbi.nlm.nih.gov/pubmed/37856516 http://dx.doi.org/10.1371/journal.pone.0277747 |