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Wnt10b protects cardiomyocytes against doxorubicin-induced cell death via MAPK modulation

BACKGROUND: Doxorubicin, an anthracycline chemotherapeutic known to incur heart damage, decreases heart function in up to 11% of patients. Recent investigations have implicated the Wnt signaling cascade as a key modulator of cardiac tissue repair after myocardial infarction. Wnt upregulation in muri...

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Detalles Bibliográficos
Autores principales:	Chen, Lei, Byer, Stefano H., Holder, Rachel, Wu, Lingyuan, Burkey, Kyley, Shah, Zubair
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586692/ https://www.ncbi.nlm.nih.gov/pubmed/37856516 http://dx.doi.org/10.1371/journal.pone.0277747

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