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New insights into the mechanochemical coupling mechanism of kinesin–microtubule complexes from their high-resolution structures
Kinesin motor proteins couple mechanical movements in their motor domain to the binding and hydrolysis of ATP in their nucleotide-binding pocket. Forces produced through this ‘mechanochemical’ coupling are typically used to mobilize kinesin-mediated transport of cargos along microtubules or microtub...
Autores principales: | Benoit, Matthieu P.M.H., Hunter, Byron, Allingham, John S., Sosa, Hernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586761/ https://www.ncbi.nlm.nih.gov/pubmed/37560910 http://dx.doi.org/10.1042/BST20221238 |
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