Proteotoxic stresses stimulate dissociation of UBL4A from the tail-anchored protein recognition complex

Inclusion body formation is associated with cytotoxicity in a number of neurodegenerative diseases. However, the molecular basis of the toxicity caused by the accumulation of aggregation-prone proteins remains controversial. In this study, we found that disease-associated inclusions induced by elong...

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Detalles Bibliográficos
Autores principales: Hagiwara, Takumi, Minami, Ryosuke, Ushio, Chizuru, Yokota, Naoto, Kawahara, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Molecular Bases of Health & Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586765/
https://www.ncbi.nlm.nih.gov/pubmed/37747814
http://dx.doi.org/10.1042/BCJ20230267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586765/
https://www.ncbi.nlm.nih.gov/pubmed/37747814
http://dx.doi.org/10.1042/BCJ20230267

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