The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission

The Endosomal Sorting Complexes Required for Transport (ESCRT) machinery mediates the membrane fission step that completes cytokinetic abscission and separates dividing cells. Filaments composed of ESCRT-III subunits constrict membranes of the intercellular bridge midbody to the abscission point. Th...

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Detalles Bibliográficos
Autores principales: Paine, Elliott L, Skalicky, Jack J, Whitby, Frank G, Mackay, Douglas R, Ullman, Katharine S, Hill, Christopher P, Sundquist, Wesley I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586806/
https://www.ncbi.nlm.nih.gov/pubmed/37772788
http://dx.doi.org/10.7554/eLife.84515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586806/
https://www.ncbi.nlm.nih.gov/pubmed/37772788
http://dx.doi.org/10.7554/eLife.84515

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