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The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission
The Endosomal Sorting Complexes Required for Transport (ESCRT) machinery mediates the membrane fission step that completes cytokinetic abscission and separates dividing cells. Filaments composed of ESCRT-III subunits constrict membranes of the intercellular bridge midbody to the abscission point. Th...
Autores principales: | Paine, Elliott L, Skalicky, Jack J, Whitby, Frank G, Mackay, Douglas R, Ullman, Katharine S, Hill, Christopher P, Sundquist, Wesley I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586806/ https://www.ncbi.nlm.nih.gov/pubmed/37772788 http://dx.doi.org/10.7554/eLife.84515 |
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