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Effect of down-regulation of let-7c/g on triggering a double-negative feedback loop and promoting restenosis

BACKGROUND: Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) are the main causes of restenosis (RS) in diabetic lower extremity arterial disease (LEAD). However, the relevant pathogenic mechanisms are poorly understood. METHODS: In this study, we introduced a "two-s...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Zhou, Xiaojun, Li, Xianzhi, Yao, Shuai, Jiang, Shan, Zhang, Rui, Zou, Zhiwei, Liao, Lin, Dong, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586861/
https://www.ncbi.nlm.nih.gov/pubmed/37433785
http://dx.doi.org/10.1097/CM9.0000000000002763