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Neuroprotective potential of intranasally delivered L-myc immortalized human neural stem cells in female rats after a controlled cortical impact injury

Efficacious stem cell-based therapies for traumatic brain injury (TBI) depend on successful delivery, migration, and engraftment of stem cells to induce neuroprotection. L-myc expressing human neural stem cells (LMNSC008) demonstrate an inherent tropism to injury sites after intranasal (IN) administ...

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Detalles Bibliográficos
Autores principales: Amirbekyan, Mari, Adhikarla, Vikram, Cheng, Jeffrey P., Moschonas, Eleni H., Bondi, Corina O., Rockne, Russell C., Kline, Anthony E., Gutova, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587115/
https://www.ncbi.nlm.nih.gov/pubmed/37857701
http://dx.doi.org/10.1038/s41598-023-44426-7