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Acamprosate reduces ethanol intake in the rat by a combined action of different drug components

Alcohol misuse accounts for a sizeable proportion of the global burden of disease, and Campral(®) (acamprosate; calcium-bis-(N-acetylhomotaurinate)) is widely used as relapse prevention therapy. The mechanism underlying its effect has in some studies been attributed to the calcium moiety and not to...

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Detalles Bibliográficos
Autores principales: Ademar, Karin, Loftén, Anna, Nilsson, Mathilda, Domi, Ana, Adermark, Louise, Söderpalm, Bo, Ericson, Mia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587117/
https://www.ncbi.nlm.nih.gov/pubmed/37857829
http://dx.doi.org/10.1038/s41598-023-45167-3