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Anti-PD-1 antibody armored γδ T cells enhance anti-tumor efficacy in ovarian cancer

γδ T cells have the unique ability to detect a wide range of tumors with low mutation burdens, making them attractive candidates for CAR-T-cell therapy. Unlike αβ T cells and other immune cells, γδ T cells are superior in MHC non-restriction, selective cell recruitment, and rapid activation. However...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Han, Jingyi, Wang, Dongdong, Cai, Menghua, Xu, Yi, Hu, Yu, Chen, Hui, He, Wei, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10587135/
https://www.ncbi.nlm.nih.gov/pubmed/37857598
http://dx.doi.org/10.1038/s41392-023-01646-7